Name: Southern Style Creamy Parmesan Chicken Pasta for Cozy Nights
Prep time: 10 min
Cook time: 30 min
Total time: 40 min
Ingredients: 4 pieces Boneless, Skinless Chicken Breasts (Pound to even thickness); 1 teaspoon Paprika (Smoked paprika for deeper flavor); 1 teaspoon Garlic Powder (Fresh garlic can be used for more flavor); 1 teaspoon Onion Powder; 1 teaspoon Dried Thyme (Italian seasoning is a great swap); 1/2 teaspoon Cayenne Pepper (Adjust for heat preference); 1 teaspoon Salt (Use kosher salt for cleaner taste); 1/2 teaspoon Black Pepper; 8 ounces Fettuccine or Penne Pasta (Can substitute with rotini or gluten-free); 4 tablespoons Butter (Ghee can be a lactose-free alternative); 2 cloves Garlic, minced (Leave out for simplicity); 1/4 cup All-Purpose Flour (Cornstarch as gluten-free alternative); 1 cup Heavy Cream (Half and half can be used for lighter version); 1 cup Whole Milk (Use skim milk for fewer calories if needed); 1 cup Freshly Grated Parmesan Cheese (Avoid pre-grated for best melt); 4 ounces Cream Cheese (softened) (Goat cheese can add a tangy flavor); 1 tablespoon Fresh Lemon Juice (White wine vinegar as alternative); 1 tablespoon Worcestershire Sauce (Soy sauce can be a different flavor); 1/2 cup Crumbled Bacon (Optional, omit for a lighter dish); 1/4 cup Green Onions, chopped; 1/4 cup Fresh Parsley, chopped; 1/4 teaspoon Red Pepper Flakes (Optional for spice lovers); to taste Fresh Cracked Black Pepper (For serving)

As I stirred the sauce, the intoxicating aroma of buttery Parmesan and seasoned chicken enveloped my kitchen, transporting me straight to a Southern family gathering. Southern Style Creamy Parmesan Chicken Pasta is that beautiful bridge between indulgence and comfort food—perfect for those moments when fast food just won’t cut it. With tender chicken bathed in a velvety cream sauce and pasta that hugs every bite, this dish transforms an ordinary weeknight into a memorable feast. It comes together quickly, making it a breeze to whip up even on your busiest nights, and it’s guaranteed to please the whole family. So, are you ready to bring Southern charm to your dinner table?

Why is this pasta recipe a must-try?

Convenience: This dish comes together in just 30 minutes, making it perfect for busy weeknights when you want a homemade meal without the hassle.

Comforting Flavors: The blend of creamy Parmesan, seasoned chicken, and tender pasta creates a symphony of taste that feels like a warm hug in a bowl.

Family-Friendly: It’s a guaranteed crowd-pleaser that’s sure to satisfy even the pickiest eaters, proving comfort food can cater to all ages.

Versatile: Switch things up by adding your favorite vegetables or swapping proteins—get creative and make it suit your family’s taste! If you love variations, check out my Parmesan Chicken Pasta or Chicken Mozzarella Pasta.

Gourmet Feel: Impress your dinner guests with this dish that looks and tastes like it’s from a high-end restaurant. You’ll feel like a gourmet chef in your own kitchen!

Southern Style Creamy Parmesan Chicken Pasta Ingredients

For the Chicken
• Boneless, Skinless Chicken Breasts – The main protein that will stay juicy and flavorful when pounded to an even thickness.
• Paprika – Adds a beautiful color and subtle smokiness; consider smoked paprika for a deeper flavor.
• Garlic Powder – Elevates every bite with its savory essence; fresh garlic can be used for a more aromatic kick.
• Onion Powder – Imparts sweetness that complements the dish wonderfully.
• Dried Thyme – Offers a fragrant herbaceous note; Italian seasoning is a great swap if you want to mix it up.
• Cayenne Pepper – Provides an adjustable kick of heat; you can omit it for a milder dish.
• Salt & Black Pepper – Essential for flavoring; use kosher salt for the cleanest taste.

For the Pasta
• Fettuccine or Penne Pasta – These shapes are perfect for holding onto the rich sauce; feel free to swap in rotini or a gluten-free cousin.

For the Sauce
• Butter – Creates a rich roux for the sauce; ghee can be a great lactose-free alternative.
• Garlic, minced – Freshly minced garlic brings added depth; leave it out if you’re keeping it simple.
• All-Purpose Flour – Thickens the sauce beautifully; cornstarch can be used as a gluten-free swap.
• Heavy Cream – Provides that luxurious creaminess; half and half is a lighter substitute if desired.
• Whole Milk – Balances the sauce’s richness; use skim milk for fewer calories, but it may alter the creamy texture.
• Freshly Grated Parmesan Cheese – Key flavoring for this Southern Style Creamy Parmesan Chicken Pasta; avoid pre-grated for the best melt.
• Cream Cheese (softened) – Boosts creaminess and richness; goat cheese can add a lovely tang.
• Fresh Lemon Juice – Brightens the whole dish; white wine vinegar works in a pinch.
• Worcestershire Sauce – Adds depth and complexity; soy sauce can be a different flavor experience.

For the Toppings
• Crumbled Bacon – Adds a crispy garnish; feel free to omit for a lighter dish.
• Green Onions & Fresh Parsley – Fresh herbs enhance the vibrancy of the dish; chives or basil are other flavorful options.
• Red Pepper Flakes – Optional, for those who enjoy an extra kick.
• Fresh Cracked Black Pepper – Use for serving to elevate the flavor just before the first bite.

Step‑by‑Step Instructions for Southern Style Creamy Parmesan Chicken Pasta

Step 1: Prepare the Chicken
Start by placing boneless, skinless chicken breasts between two sheets of plastic wrap or parchment paper. Gently pound them to an even thickness of about ¾ inch for uniform cooking. In a small bowl, mix paprika, garlic powder, onion powder, thyme, cayenne, salt, and pepper. Coat the chicken pieces with this spice blend, ensuring they are well covered for maximum flavor.

Step 2: Cook the Chicken
Heat 2 tablespoons of olive oil in a large skillet over medium-high heat. Once the oil is shimmering, carefully add the seasoned chicken breasts. Sauté for 6-7 minutes on each side until they’re golden brown and reach an internal temperature of 165°F. Once cooked through, transfer the chicken to a plate to rest before slicing it into bite-sized pieces.

Step 3: Cook the Pasta
In a large pot, bring a generously salted water to a boil. Add your choice of fettuccine or penne pasta and cook according to package instructions until al dente, about 8-10 minutes. Reserve 1 cup of pasta water before draining the pasta, and set the drained pasta aside. This water will help adjust the sauce consistency later for your Southern Style Creamy Parmesan Chicken Pasta.

Step 4: Make the Roux
In the same skillet used for the chicken, melt 4 tablespoons of butter over medium heat. Once melted, whisk in ¼ cup of all-purpose flour, stirring continuously for about 2 minutes, allowing it to take on a light golden color. This roux will thicken your sauce and add a rich depth to the creamy finish of the dish.

Step 5: Build the Sauce
Gradually whisk in 1 cup of heavy cream and 1 cup of whole milk to the roux. Continue to whisk until the mixture is smooth and begins to simmer gently, which should take about 3-5 minutes. Add in the Worcestershire sauce, stirring to combine, while watching for that comforting, rich flavor to develop in your Southern Style Creamy Parmesan Chicken Pasta sauce.

Step 6: Incorporate Cheeses
Once the sauce is simmering, reduce the heat to low and remove the skillet from the burner. Whisk in 4 oz of softened cream cheese and 1 cup of freshly grated Parmesan cheese until both are fully melted and integrated into the sauce. This rich blend will create the creamy texture that envelops the chicken and pasta beautifully.

Step 7: Finish the Sauce
Stir in the juice of one fresh lemon, which brightens the sauce wonderfully. Season with additional salt and pepper to taste. The sauce should have a creamy consistency—smooth and velvety. Ensure it’s just right, as this will be the heart of your Southern Style Creamy Parmesan Chicken Pasta dish.

Step 8: Combine
Add the drained pasta to the sauce, using tongs to carefully toss the pasta until it is completely coated. If the sauce feels too thick, gradually add reserved pasta water, a little at a time, to achieve your desired consistency. This step ensures every noodle is perfectly enveloped in that luxurious sauce.

Step 9: Serve
Plate the creamy pasta mixture onto individual serving plates. Top each serving with the sliced chicken and, if desired, garnish with crumbled bacon, fresh green onions, and parsley for a pop of color. Finish off with an extra sprinkle of Parmesan and a dash of red pepper flakes for those who like a touch of heat before serving immediately.

What to Serve with Southern Style Creamy Parmesan Chicken Pasta

Imagine the warmth of a family gathering, complete with delicious aromas and hearty, comforting fare.

Garlic Bread: Perfect for soaking up any leftover sauce, adding a crunchy contrast to the creamy pasta.
Simple Green Salad: A fresh, crisp salad with a light vinaigrette brightens the meal and balances the richness of the dish perfectly.
Roasted Vegetables: Seasonal veggies like Brussels sprouts or asparagus provide a lovely caramelized flavor, adding healthful color and texture to your plate.
Coleslaw: A tangy slaw brings a refreshing crunch to the table, enhancing the comforting flavors of the creamy pasta with its crunch.
Honey Butter Biscuits: Soft, flaky biscuits brushed with honey butter elevate this meal to a true Southern feast, making every bite feel special.
Sweet Tea or Lemonade: These quintessential Southern drinks add a refreshing sweetness that pairs beautifully with the savory pasta.
Chocolate Mousse: End the meal on a sweet note; the rich, silky mousse complements the creamy dish without feeling too heavy.
Crispy Fried Pickles: For a fun appetizer, these give a delightful crunch and an unexpected tang that pairs beautifully with your savory main course.

Make Ahead Options

Preparing Southern Style Creamy Parmesan Chicken Pasta in advance is a game-changer for busy weeknights! You can marinate the chicken with spices up to 24 hours ahead of time, allowing those flavors to deeply infuse. Additionally, you can cook the pasta and store it in an airtight container in the refrigerator for up to 3 days. The sauce can also be made ahead, but remember to store it separately to maintain its creamy texture. When you’re ready to serve, simply reheat the sauce gently on the stovetop, adding a splash of milk if necessary, then combine everything just before enjoying your comforting meal with minimal effort!

How to Store and Freeze Southern Style Creamy Parmesan Chicken Pasta

Fridge: Store leftover Southern Style Creamy Parmesan Chicken Pasta in an airtight container for up to 3 days. Ensure it’s cooled before sealing to maintain freshness.

Freezer: If you plan to freeze it, portion the pasta into freezer-safe containers. It can be frozen for up to 2 months. To reheat, thaw overnight in the fridge before warming gently on the stovetop or in the microwave, adding a splash of cream if needed.

Reheating: When reheating, do so gently to avoid separating the creamy sauce. Adding a little reserved pasta water or milk can help restore its luxurious texture.

Wrap Tight: If you’re storing in the freezer, wrap the containers tightly to prevent freezer burn and ensure your comforting meal remains as delicious as the day you made it!

Expert Tips for Southern Style Creamy Parmesan Chicken Pasta

Pound Evenly: Ensure the chicken breasts are pounded to a uniform thickness; this guarantees even cooking and juicy results, avoiding dry spots.
Fresh Ingredients: Opt for freshly grated Parmesan cheese. This will melt beautifully and enhance the creaminess of your Southern Style Creamy Parmesan Chicken Pasta, unlike pre-grated varieties.
Pasta Water Magic: Remember to reserve pasta water! It’s a magical ingredient that can adjust the sauce’s consistency, creating that perfect silky texture.
Taste as You Go: Don’t forget to taste and adjust seasoning throughout! A pinch more salt or a splash of lemon juice can elevate the flavors remarkably, making it truly irresistible.
Adapt for Spice Lovers: If you enjoy heat, don’t hesitate to increase the cayenne and red pepper flakes while cooking; just be sure to check with your family first to suit everyone’s taste.

Southern Style Creamy Parmesan Chicken Pasta Variations

Customize your Southern Style Creamy Parmesan Chicken Pasta to delight your taste buds with these tempting variations!

Gluten-Free: Substitute regular pasta with gluten-free options like chickpea or brown rice pasta to accommodate dietary needs.
Veggie-Packed: Add fresh spinach, sun-dried tomatoes, or peas for a pop of color and a nutritious boost that complements the cream sauce beautifully.
Spice It Up: Introduce jalapeños or a dash of hot sauce for an exciting kick, transforming this dish into a spicy Southern delight.
Herb-Infused: Swap dried thyme for fresh herbs like basil or parsley to elevate the dish with fresh flavors, taking your pasta to the next level.
Seafood Fusion: Use shrimp or scallops instead of chicken for a delightful seafood twist—imagine each forkful revealing tender morsels of ocean goodness!
Creamy Vegan Option: Substitute chicken with grilled mushrooms or chickpeas, use coconut milk instead of cream, and nutritional yeast in lieu of Parmesan to create a rich and creamy vegan version.
Cheesy Trio: Go wild with cheese by adding mozzarella or gouda to the sauce along with Parmesan, creating a delightful three-cheese blend that will keep cheese lovers absolutely happy.

If you’d like more inspiration, feel free to explore my Chicken Mozzarella Pasta or the indulgent flavors of Air Fryer Parmesan. Enjoy the cooking adventure!

Southern Style Creamy Parmesan Chicken Pasta Recipe FAQs

What is the best way to select ripe chicken for this recipe?
Absolutely! When choosing chicken breasts, look for ones that are plump and have a pinkish hue. Avoid those with dark spots or a slimy texture. Fresh chicken should feel firm and not have a strong odor. If possible, buy from a trusted butcher or choose organic options for better flavor and quality.

How should I store leftovers of Southern Style Creamy Parmesan Chicken Pasta?
Store any leftovers in an airtight container in the fridge for up to 3 days. Be sure to let the pasta cool before sealing it in the container to help maintain freshness. If reheating, a splash of milk or cream can restore its creamy texture!

Can I freeze Southern Style Creamy Parmesan Chicken Pasta?
Yes, you can freeze this dish for up to 2 months! To do this, divide the pasta into individual portions and place them in freezer-safe containers. When ready to enjoy, thaw overnight in the refrigerator, then reheat gently on the stovetop or microwave, adding cream or reserved pasta water if the sauce is too thick.

What should I do if the sauce is too thick when reheating?
Very! If you find your sauce thickens too much after refrigeration, don’t fret. Simply add a splash of milk, cream, or some reserved pasta water while gently reheating. Stir continuously until the sauce reaches your desired consistency. This simple trick can bring your Southern Style Creamy Parmesan Chicken Pasta back to its glorious creaminess!

Is this dish suitable for gluten-free diets?
Absolutely! You can easily adapt this recipe by substituting the pasta with gluten-free varieties like rice pasta or gluten-free penne. Just be sure to check that all other ingredients, particularly the flour, are gluten-free as well. Always consult with any dietary considerations to ensure the dish meets your guests’ needs.

Can my pets share in the leftover Southern Style Creamy Parmesan Chicken Pasta?
While the chicken itself is safe for pets, I’d recommend avoiding sharing the pasta with your furry friends. The cheese and spices like garlic and onion can be harmful to them. Instead, offer them plain cooked chicken in moderation, and save the creamy goodness for yourself!