In a medium bowl, combine Greek yogurt, light mayonnaise, ketchup, yellow mustard, and pickle relish to make the special sauce.

In a large skillet, heat lean ground beef over medium-high heat, breaking it apart and seasoning with garlic powder, onion powder, Worcestershire sauce, salt, and pepper. Cook until browned.

Warm high-protein wraps in the microwave or skillet to make them pliable.

Lay each wrap flat, spread special sauce, add beef, lettuce, cheese, pickles, and onion. Fold and roll tightly.

Optional: Toast wraps in a skillet until golden brown for extra crispness.